

Jeremy ends up getting caught by Chloe's boyfriend halfway through sex. The two friends attend a house party, where Jeremy hooks up with Chloe Valentine, but upon taking ecstasy the squip goes haywire and begins speaking in Spanish. Jeremy's squip obliges to help Michael also be cool after a lengthy conversation with Jeremy. Jeremy also gains the attention of Christine through their school play rehearsals. Jeremy sees rapid progress at school, gaining friendship with Rich and skipping class to make out with Brooke, another popular girl, but slowly degrades his friendship with Michael. Jeremy's squip quickly goes to work with transforming Jeremy to be more "cool." by picking up some new clothes in the mall and changing his behavior, but a chance encounter with Chloe, one of the most popular girls in the school soon turn hers attention to Jeremy in a conversation guided by Jeremy's squip. He later picks up the pill after meeting the dealer's cousin in the back of the shoe store, and upon ingestion meets his squip for the first time telepathically (in the voice of Keanu Reeves as the default avatar). Jeremy proceeds to save up money by visiting his Aunt Linda's to clean her roof gutter but to also sell some of her Beanie Baby collection on eBay. Jeremy is informed by Rich that he received his squip from a guy at the local bowling alley, but upon meeting the dealer on a later day notifies Jeremy that he is out of stock and directs Jeremy to his cousin, a supplier working at the local Payless shoe store in the Menlo Park Mall. Rich mentions to Jeremy that he regrets bullying him but it was at the direction of his squip in order to climb through their school social ladder, and that he was also a loser like Jeremy in the previous school year prior to acquiring a squip. Rich finds Jeremy at a school Halloween party and reveals to Jeremy that the object he's after is known as a "squip," a supercomputer in the form of a pill that can communicate directly to the brain. Rich Goranski is a short-statured but well-built part of the popular teen group that bullies Jeremy. Michael tells Jeremy that he's vaguely heard of a pill that can improve someone’s life he thinks it's called a "script" and he suspects his brother used one to get a high SAT score. Jeremy plans to implement his plans as he and Christine both practice for their school play, Shakespeare's A Midsummer Night's Dream. His main goal in life is to get Christine to notice him, then date her. Jeremy is tired of being a loser and hopes to find a way to change this. They sit together at lunch and talk about Jeremy's attempts at wooing his longtime crush, Christine Caniglia. Jeremy's best friend is the music-loving Michael Mell.

Jeremy is considered a loser by many of his peers the popular girls have no interest in him, and he is constantly bullied. It is written in the first person, from the perspective of high school student Jeremiah “Jeremy” Heere. Be More Chill takes place in Metuchen, New Jersey.
